The Joint-Brain Axis: Insights From Rheumatoid Arthritis on the Crosstalk Between Chronic Peripheral Inflammation and the Brain

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by erosive polyarthritis.Beyond joint pathology, RA is associated with neuropsychiatric comorbidity including depression, anxiety, and an increased risk to develop neurodegenerative diseases in later life.Studies investigating the central nervous system (CNS) in preclinical m

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Micro Aspheric Convex Lenses Fabricated by Precise Scraping

An easy, fast, inexpensive, and simple method utilizing a microshaper with a very small knife nose is used to fabricate microconvex aspherical lenses.The microshaper is mounted on a computer numerical control (CNC) machine.To achieve an accurately designed profile of the lens surface, a cutter-path planning algorithm with compensation for knife int

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